Tag Archives: Massachusetts Institute of Technology

New survival and growth technique for adult stem cell discovered

Here comes a new technique capable of encouraging the survival and growth of adult stem cell! Hats off to the U.S. scientists for creating this technique. This is a step forward towards the therapeutic use of such cells. Being the precursor cells for specific cell types, these adult stem cells can hold great promise for treating injuries and diseases. Certain growth factors – when presented in the right physical context — encourage the survival and proliferation of bone marrow mesenchymal stem cells that are grown outside the body. This is shown by a biological engineering Professor Linda Griffith-led team of Massachusetts Institute of Technology scientists. This new research ignites hope for a future when stem cells — removed from a patient — could be transplanted to an injury site. This eventually will induce the new cells to grow into new, healthy tissue.

New inexpensive and fast bedside diagnostic tools

Gone are the days when boffins had to wait for days and part with hefty bucks for multiplexed detection of biomolecules. The Massachusetts Institute of Technology (MIT) chemists have come up with a cheaper and high-throughput method by using multifunctional particles. The new particle contains a barcoded ID and one or more probe regions which would turn fluorescent when it detects targets in a test sample. It may also prove handy in drug discovery or genetic profiling, researchers feel. The single-probe encoded particles used in the multiplexed analysis were loaded with DNA oligomer probes. Providing some clus on the new diagnostic tools, researchers explained, As two streams of monomers (liquid precursors loaded with fluorescent dye or molecular probe) flow side by side through a microfluidic device, ultraviolet light repeatedly strikes the streams. A chemical reaction initiated by the light causes the liquid to solidify, forming a single particle with two distinct ends. Each particle takes on the shape of a “mask” (similar to a transparency film) through which the UV light is aimed. One end of each particle is a fluorescent “dot-pattern” barcode that reveals what the target molecule of the particle is, and the other end is loaded with a probe and only turns fluorescent if the target molecule is present. The particles can also be designed to each test for multiple targets, by adding several unique regions.