Something to cheer for Generex Biotechnology Corporation. Mexican Institute of Industrial Property has granted a new patent to Generex called Pharmaceutical Compositions for Buccal and Pulmonary Application. The patent is with regard to the process, composition and methodologies for the purpose of delivery of macromolecules via the buccal cavity of the mouth. The patent is related to improved pharmaceutical composition which comprises macromolecule pharmaceuticals in micellar form and is effective in pulmonary and buccal application . The claim is also related to procedures for preparing and using pharmaceutical compositions. The methods used for enhancing the rate of absorption of a macromolecular pharmaceutical agent have also been disclosed.
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Generex Biotechnology Corporation is conducting human clinical trials of Antigen Express synthetic avian influenza vaccine which is being regarded as one of the first studies to be conducted on man. For conducting trials, the company has entered into an agreement with Lebanese-Canadian Hospital based in Lebanon. Pre clinical trials are already going on since 2004. Peptide-synthesis technology was used for developing this vaccine and it successful it would emerge out as a cost effective treatment. The vaccine comprises of specific fragments of H5 protein extracted from the H5N1 influenza virus which has been modified for enhancing their potency in stimulating CD4+ T helper cells. With bird flu virus spreading at a fast pace and causing a lot of destruction, it is necessary that effective vaccine should be developed for curbing the flu and this trial is a step towards achieving it.